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Tramadol is a synthetic opioid analgesic drug that is used to treat moderate to moderately severe pain. It works by blocking certain chemicals (receptors) in the brain that transmit pain signals. It is often prescribed for patients who have chronic pain due to cancer, arthritis, or fibromyalgia.
Tramadol was first approved by the FDA in 1995 and is currently available over-the-counter in many countries around the world. However, it is still considered a controlled substance in the United States.
The active ingredient in tramadol is called O-desmethyltramadol. It is metabolized by the liver enzyme CYP2D6 into its major active metabolite M1. M1 binds to mu receptors in the central nervous system (CNS), where it produces its effects.
In addition to being an effective painkiller, tramadol is also a mild tranquilizer. It may cause side effects such as nausea, dizziness, dry mouth, constipation, blurred vision, sweating, and vomiting. These symptoms should go away after a few hours. If they do not, consult your doctor immediately.
Tramadols are generally safe for short term use. However, long term use can lead to dependence and addiction. In fact, some people develop a tolerance to tramadol, meaning that they need higher doses to achieve the same effect. This makes them less likely to stop using the drug once they start taking it regularly.
Tramadole can be taken orally or injected intravenously. Oral ingestion is the preferred method of administration. Intravenous injection is only recommended if oral intake is ineffective or impractical.
There are several different brands of tramadol available. Each brand contains varying amounts of the active ingredients. The amount of each ingredient varies depending on how much of the drug is produced by the body.
Tramadolic acid is a metabolite of tramadol. It is present in trace amounts in the blood stream. Its primary function is to help prevent overdose.
Tramadolo hydrochloride is a salt of tramadol. Like tramadol, it is an opioid analgesic. It is used to treat moderate pain.
Tramadone is a generic version of tramadol. Generic drugs are identical to their branded counterparts in dosage, safety profile, effectiveness, and any known side effects.
Tramadix is a combination product containing both tramadol and acetaminophen. It is used to relieve moderate to moderately severe pain and fever.
Tramal is a combination product containing tramadol and paracetamol. It is used to reduce fever and pain.
Tramalin is a combination product containing acetaminophen and codeine. It is used to control moderate to moderately severe pain caused by injury or surgery.
Tramal-A is a combination product containing amitriptyline and acetaminophen. Amitriptyline is an antidepressant medication. Acetaminophen is an anti-inflammatory agent.
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